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Novel drug targets based on metallobiology of Alzheimer's disease.

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2010 Nov Others S Bandyopadhyay, X Huang, DK Lahiri… - Expert opinion on …, 2010 - Taylor & Francis

Full Author : ['Bandyopadhyay, Sanghamitra', 'Huang, Xudong', 'Lahiri, Debomoy K', 'Rogers, Jack T']
Journal Title : Expert opinion on therapeutic targets
Chapter : Section8
Journal Year : 2010
Cited by : 61

IMPORTANCE OF THE FIELD: Increased localization of Zn, Fe, Cu and Al within the senile plaques (SP) exacerbates amyloid beta (Abeta)-mediated oxidative damage, and acts as catalyst for Abeta aggregation in Alzheimer's disease (AD). Thus, disruption of abe..... Read More

Keywords : ['novel drug target base', 'alzheimers disease', 'metallobiology']
PubMed Link : https://www.tandfonline.com/doi/abs/10.1517/14728222.2010.525352
Google Scholar Link : https://scholar.google.com/scholar?cites=5063184045596086743&as_sdt=2005&sciodt=0,5&hl=en&num=20